Everything you need for DNA origami projects
DNA origami is a technique that allows the construction of objects at the nanometer scale.
DNA double-helices are the basic building blocks for these objects connecting to form a rich diversity of shapes ranging from simple bricks to intricate objects. The absolute dimensions of these objects may range to hundreds of nanometers. They have precise used-defined features and are chemically registered.
It is possible to install a variety of chemical functionalities at virtually any position on the target object. The objects are encoded in DNA sequences and form, in solution, through sequence-programmed self-assembly.
Eurofins Genomics offers everything required for a successfull DNA origami experiment:
References & Protocols for usage:
(1) Rothemund, PWK: "Folding DNA to create nanoscale shapes and patterns" -- Nature. 2006 Mar 16; 440(7082):297-302
(2) Douglas, SM; Dietz, H; Liedl, T; Högberg, B; Graf, F; Shih, WM: "Self-assembly of DNA into nanoscale three-dimensional shapes" -- Nature. 2009 May 21; (459(7245):414-418)
(3) Castro CE, et al: “A primer to scaffolded DNA origami” — Nature Methods. 2011 Mar; 8(3):221-9
Scaffold DNA for your research
Eurofins, in partnership with tilibit supplies specialised materials for nucleic acid nanotechnology. We provide high quality, hard to find materials in the right form and in the quantity you need, at affordable prices.
Ultrapure, single-stranded scaffold DNA of various lengths is available for synthesising mass quantities of DNA origami. We also offer origami nano-prep ‘kits’ with several essential components that simplify and reduce the cost of self-assembly experiments.
Order scaffold DNA for your project now at >> Eurofins Genomics
Design and synthesis of DNA origami objects
Tilibit offers custom engineering services ranging from simple design tasks to full application development.
Tilibit use their its experience in selecting and optimising reaction conditions to ensure high-yield and high-quality production of nanodevices. Post-synthesis steps may include purification, structural and/or compositional analysis, chemical modifications, or construction of higher-order objects through multimerisation.
Tilibit can build and modify products using any, or all of these steps. We offer a library of prefabricated DNA nanostructure designs with validated shapes and functionalities. We can also develop novel DNA nanostructure designs according to your specifications and tailored to your specific application. As with our prefabricated designs, we can fold the designed structures for you, purify them, and perform quality control. If you would like to tell us more about your project, we will explore how tilibit can help you.