We offer more than 100 different modifications and provide oligos with multiple modifications or combinations of various modifications. Please be aware that the yield of oligos with multiple modifications is usually lower than those with fewer modifications.
The more you increase the number of modifications, combinations of modifications and the sequence length, the more complex the synthesis and purification of your oligonucleotide becomes. If you want to order multiple modified oligonucleotides, please contact our customer support team for advice.